Cetero Research, the leading provider of clinical pharmacology services, specializes in providing safety-minded research solutions for Phase I and IIa trials. Our focus on safety ensures your small or large molecule receives the necessary attention to detail. With over 25 years of experience in clinical pharmacology, we have the knowledge and medical expertise to conduct these important studies.

We have expertise in the following types of studies:

• First-in-Human
  • Single and multiple ascending dose in healthy participants or patients
• Proof-of-Concept
• Interaction
  • Drug-drug, drug-food, and alcohol interaction
• Bioavailability
  • Absolute bioavailability, bioequivalence
• Pharmacokinetic (PK)
  • Dose proportionality, age/gender, renal or hepatic-impaired
• Pharmacodynamic (PD)
  • Objective or subjective measures performed in-house or with patient diaries
• Thorough QT

Cetero’s Approach to Clinical Pharmacology – Safety While Meeting Your Objectives

Cetero’s primary objective is to consistently evaluate the safety profile of the compound in question while always ensuring the well-being of our study participants. As such, our staff is trained on the latest medical safety equipment and we ensure our staff have current Advanced Cardiac Life Support (ACLS) training. In a number of our units we have staff paramedics present throughout the duration of the study. Also, we have conducted mock Serious Adverse Event (SAE) drills to ensure all our staff and paramedics are ready to handle any adverse events that may occur – with local hospitals between five and 10 minutes of each of our facilities. 

Cetero’s Clinical Facilities and Experience

Our five North American clinical pharmacology units are purpose-built, state-of-the-art facilities.  Each facility has an intensive care unit that enables 24/7 monitoring of the study participants.

We have experience in a number of therapeutic classes, medical devices, vaccines and biologics. Our experience includes:

• Cardiovascular
• Dermatology
• Endocrinology
• Gastroenterology
• Immunology
• Medical devices
• Nephrology
• Neurology
• Ophthalmology
• Respiratory
• Rheumatology
• Vaccines
• Simple and complex biologics including monoclonal antibodies